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Acetaminophen warning: FDA warns against dosages above 325 mg

Acetaminophen warning: FDA warns against dosages above 325 mg.
Acetaminophen warning: FDA warns against dosages above 325 mg.
Photo by Brendan Smialowski/Getty Images

Acetaminophen warning from the FDA was issued today. The agency has asked doctors not to prescribe drugs containing more than 325 mg. According to Fox News on Jan. 16, dosages above that amount can result in liver damage.

The agency said in a statement Tuesday that limiting the amount of acetaminophen per dosage unit will reduce the risk of severe liver damage from an inadvertent acetaminophen overdose, which can lead to liver failure, liver transplant, and death.

Acetaminophen warning specifically states that there is no data to support any additional benefit to patients when administering dosages in excess of 325mg. When taken in small doses, the drug ingredient is considered harmless.

A popular drug containing acetaminophen to treat pain, such as Tylenol, is known as a "combination drug." Manufacturers of combination drugs were asked by the FDA in 2011 to restrict levels of acetaminophen to 325 mg by Jan. 14 of this year. More than half of manufacturers complied, although drugs containing higher doses still remain on the market today.

Last year additional stories about acetaminophen warnings were covered here, "Acetaminophen warning: FDA adds deadly skin disease as side effect" and here "Tylenol warnings: Red label on cap warning of potential death risk."

What do you think about the Acetaminophen warning story? Please drop in your comments below.

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