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A study on mast cell tumors in cats

I look up to you for my safety
Karla Kirby

Unfortunately, cats are susceptible to mast cell tumors. Mast cells are in attendance in most tissues, and are particularly lining of the lungs, mouth, nose, major in the skin, and

.They are a significant component of the immune system, with roles in inflammation and allergy reactions.

Mast cell tumors are shaped by the abnormal proliferation of mast cells, and when the complete body is affected, the disease is called Mastocytosis. Mast cells can release several biologically active chemicals such as heparin and histamine, which can be extremely damaging to the body when released in surplus by the tumor cells.

There are two separate forms of skin MCTs in cats: Mastocytic MCTs that resemble those in dogs and Histiocytic MCTs. The mastocytic MCTs can be additionally classified into diffuse and compact; the diffuse form has a more malignant (cancerous) behavior, whereas the compact form is estimated to influence 50-90% of the cases and is associated with a more benign behavior

MCTs are the second most common skin tumor in the feline, accounting in the region of 20% of all skin tumors. The typical age of diagnosis for typical MCTs is 10 years and for histiocytic MCTs just 2.4 years. More than a few studies propose that Siamese cats
may be at higher risk of developing MCTs of both types. MCTs of the internal organs such as intestines or spleen are more common in cats than dogs...

Skin MCTs are typically detected by owners as solitary, firm, raised, hairless lumps on the skin. These lesions are generally white, or less normally pink. Other forms that have been described are flat, plaque-like lesions. Roughly 20% of cats with MCTs will have multiple nodules and approximately 25% will have some ulceration of the masses present. In dissimilarity to dogs, the neck and head are the most familiar sites for MCTs in the cat, followed by the limbs, trunk, and other varied sites. Tumors situated on the head often involve the base of the ear and on the odd occasion affect the mouth. Affected felines are as a rule otherwise healthy.

Cats with disseminated MCTs in the spleen or intestine will often show symptoms such as anorexia, weight loss, depression, and intermittent vomiting. Intestinal MCTs will often cause bloody stools and fever as well. Physical examination of the spleen and intestines may disclose present masses. Further symptoms may be present because of the release of granules contained in the mast cells, including hard breathing, gastrointestinal ulceration, and uncontrollable hemorrhage

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