1) Horace Lawson Hunley - A confederate marine engineer, Hunley invented the first combat submarine. A vessel he had invented sank, drowning Hunley, along with the rest of the crew.
2) William Nelson (ca. 1879−1903) was a General Electric employee. He became well-known after he invented a new method of motorizing bicycles. While the New York Times regarded him as an "inventor of promise", he was apparently not as great a rider, since he was killed after he fell off one of his own bikes during a test run.
3) Sylvester H. Roper - was a prolific inventor with numerous patents. He built the steam carriage, shotgun choke, revolver repeating shotgun, and possibly even the very first motorcycle, which got him into the Motorcycle Hall of Fame in 2002. He was also the inventor of the steam-powered bicycle. He died of a heart attack and/or crash in 1896. It is unclear which came first, the heart attack or the crash.
4) Ismail ibn Hammad al-Jawhari (died ca. 1003–1010), a Muslim scholar, well-known for having written the Arabic dictionary Taj al-Lugha wa Sihah al-Arabiya, "The Crown of Language and the Correct Arabic." He died after presumably attempting to develop a glider of his own with two wooden wings and a rope, leaping from the roof of a mosque.
5) Jean-François Pilâtre de Rozier - a French chemistry and physics teacher, as well as a pioneer in the field of aviation. He also became officially known as the first aviation-related fatality when he crashed his balloon in 1785 while attempting to crash the English Channel.
6) Otto Lilienthal (1848–1896) - A pioneer of aviation who, following several successful flights, became known in the aviation field itself as "The Father of Flight." Unfortunately, he died after his glider stalled and plunged 50 feet.
7) Franz Reichelt (1879–1912) - an important inventor and pioneer of parachuting. He famously plummeted to his doom from the Eiffel Tower during an attempt to test a parachute he had designed. While his first experiments with test dummies proved successful, he was not so lucky.
8) Henry Smolinski (died 1973) - A trained engineer who left his job to attempt to bring a flying car into the market. Smolinski died when his experimental flying car, the AVE Mizar, modeled after the Ford Pinto, crashed.
9) Michael Dacre (died 2009, age 53) This is one of our more recent deaths, having happened around 4 years ago. Dacre invented the AVCEN Jetpod. Following a launch of its prototype, manned by Dacre himself, the vehicle crashed, killing him.
10) William Bullock (1813–1867) - A gifted inventor, he is most famous for having invented the rotary press. His foot was crushed during one of their installations. This did not itself kill him, until his foot developed gangrene, eventually killing him.
11) Thomas Andrews - An important chemist and mechanical engineer, Andrews was part of the team of chemists who first developed tetraethyllead as well as CFCs. Following a crippling bout of polio, he developed a series of pulleys and strings which allowed him to get out of bed. At the age of 55, he became tangled in the ropes, which strangled him to death.
12) Max Valier (1895–1930) - Invented a rocket car with liquid propulsion. The rocket, filled with alcohol, exploded as it sat on his test bench, killing him.
13) Frederick Samuel Duesenberg (December 6, 1876 – July 26, 1932) was a sportsman design engineer and manufacturer. He died on July 25th, 23 days after his car overturned during an accident while he was driving his eponymous Duesenberg(the first American car to wind the Grand Prix in France, in 1921) on a wet Lincoln Highway Road. While he was initially expected to survive his spinal injury and dislocated shoulder, he developed pneumonia, which eventually killed him.
14) Thomas Andrews (shipbuilder) (7 February 1873 – 15 April 1912) - a shipbuilder and Irish businessman, as well as the architect for none other than the Titanic. He himself was aboard the ship when an iceberg caused it to sink in 1912.
15) Alexander Bogdanov (22 August 1873 – 7 April 1928) - A Russian philosopher, fiction author, physician and Marxist revolutionary. Bogdanov believed that it was possible to achieve eternal youth through blood transfusions. Many believe that he died from blood incompatibility, which was not well-understood at the time.
16) Marie Curie (1867–1934) - died of aplastic anemia from prolonged exposure to ionizing research materials. Having discovered the process by which radium is isolated, she was poisoned by her materials and died.
17) Sabin Arnold von Sochocky - also died from aplastic anemia because of radiation exposure. Sochocky invented the world's very first radium-based luminiscent paint.
18) Karel Soucek (19 April 1947 – 20 January 1985) - A Canadian stuntman who invented a kind of shock-absorbent barrel for what Evel Knievel had referred to as the most dangerous stunt he'd ever seen. He is reported to have even attempted to convince Karel not to go through with it. A water tank was supposed to cushion his fall, but his barrel hit the rim, severely injuring him. He died shortly thereafter.
19) Valerian Abakovsky (1895–1921) - Invented the "Aerowagon." This was an experimental railcar with a rocket engine. Sounds like trouble from the beginning, does it not? It worked well at first, arriving at its initial destination, but it derailed as it returned to Moscow, killing Abakovsky, as well as the rest of the crew.
20) Li Si (208 BCE) - Li Si was Prime Minister during the Qi dynasty. He invented the Five Pains method of execution. Li Si was accused of treason, and tortured until he confessed. He was then subjected to his own method of capital punishment, the Five Pains.
21) James Douglas, 4th Earl of Morton (1581) - Invented the Scottish Maiden. This was a kind of early form of the guillotine. Douglas was accused of murdering Henry Stuart by the brother inlaw of John Knox. Douglas was arrested and eventually executed by the Scottish Maiden.
22) Aurel Vlaicu - was an engineer, pilot and inventor. He was killed when he tried to cross the Carpathian Mountains in an airplane he built himself.
23) Perillos - A metal worker who invented the "brazen bull." This brutal instrument of torture and execution was shaped like a bull, as the name implies, and after placing a prisoner inside, a fire was lit under it. The tyrant Phalaris, in order to test out this invention, put Perillos inside the bull itself.
Information retrieved from: http://en.wikipedia.org/wiki/List_of_inventors_killed_by_their_own_inven...